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Valproate is contraindicated during pregnancy in women being treated for prophylaxis of migraine headaches.

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Since patients were also treated with other antiepilepsy drugs, it is not possible, in most cases, to determine whether the following adverse reactions can be ascribed to divalproex sodium alone, or the combination of divalproex sodium and other antiepilepsy drugs.

When divalproex sodium capsules (sprinkle) are used in this patient group, they should be used with extreme caution and as a sole agent.

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Divalproex (a derivative of valproate or valproic acid) is a prescription medication used to treat seizures and manic episodes in people with bipolar disorder and to prevent migraines.

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Equivalent oral doses of valproic acid and divalproex sodium preparations (but not extended-release tablets) deliver equivalent amounts of valproate ion systemically following oral administration.

The focus of the current studies was to determine if either a cannabinoid agonist, oral THC, or a mood stabilizer, divalproex, would attenuate a broader range of marijuana withdrawal symptoms than the antidepressants.

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