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Incident heart failure in relation to vascular disease: Insights from the Health, Aging, and Body Composition Study.

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Slowing of the to make pumping of the heart more efficient, as does lowering BP which the drug dose.

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In addition, certain diuretics, notably spironolactone (Aldactone, generic), block aldosterone, a hormone involved in heart failure.

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If hypoperfusion or symptomatic hypotension (other than fleeting orthostatic symptoms) persists, the dose of the beta blocker must be reduced, or the drug must be discontinued ().

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Weaning from inotropic support and concomitant beta-blocker therapy in severely ill heart failure patients: take the time in order to improve prognosis.

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Carvedilol therapy also resulted in significant improvement in left ventricular ejection fraction and sense of well-being.

Carvedilol is available in controlled release capsules which are to be swallowed whole once a day with food and a full glass of water.

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In light of the beneficial effect of carvedilolon the progression of heart failure, and its unique multi-actionsthat are not shared by any other β-blocking drug or by any otheragent currently used in the treatment of heart failure, our findingsrepresent an important new mechanism of improved cardiac function.

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