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Now I don't discount anecdotal reports but if it was really effective there would be more than anecdotal reports - and I feel the potential interaction would be better known.

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We hypothesized that when used in combination with an angiotensin receptor blocker (ARB) olmesartan medoxomil, hydrochlorothiazide (HCTZ) will be as effective as the dihydropyridine calcium channel blocker (CCB) amlodipine to lower both clinic and 24-h ambulatory blood pressure (BP).

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BENICAR HCT and more frequently than placebo included nausea (3% vs 0%), hyperuricemia (4% vs 2%), dizziness (9% vs 2%), and upper respiratory tract infection (7% vs 0%).

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If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.

This list is not complete and many other drugs can interact with amlodipine and perindopril.

Clinicians should strive to use antipsychotics or antidepressants with a lower risk of QTc prolongation in patients with multiple risk factors for this adverse event.

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It is commonly prescribed for heart arrythmias, angina or chest pain and hypertension or high blood pressure.

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No dose adjustment is necessary for patients with mild-to-moderate disease.

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My guess is that it's probably one of the cheaper brands of drugs for high blood pressure.

Use in LIFE-THREATENING emergencies when no safer drug available.

Negative effects can be detected in vitro, but such effects have not been seen in intact animals at therapeutic doses.

Topical diclofenac is available in a solution, gel, and patch.

Co-administration of amlodipine with cimetidine did not alter the pharmacokinetics of amlodipine.

Hydrochlorothiazide may raise the serum uric acid level due to reduced clearance of uric acid and may cause or exacerbate hyperuricemia and precipitate gout in susceptible patients.

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Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation.

The results with amlodipine differ from those reported in trials of other calcium-channel blockers in patients with chronic heart failure.

In clinical trials with CADUET, no adverse reactions peculiar to this combination have been observed.

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